Pune, India, June 2018 /BIR Press Release/- Business Industry Reports announces the publication of its research report – Global Insulin Glargine Market Research Report 2018
Insulin Glargine Market is a long-acting basal insulin analogue, given once daily to help control the blood sugar level of those with diabetes. It consists of microcrystals that slowly release insulin, giving a long duration of action of 18 to 26 hours, with a "peakless" profile. Pharmacokinetically, its steady action can supplement the variable insulin secretion of non-diabetic pancreatic beta cells. Sometimes, in type 2 diabetes and in combination with a short acting sulfonylurea .
Insulin Glargine Market can help offer moderate control of serum glucose levels. In the absence of endogenous insulin—type 1 diabetes, depleted type 2 or latent autoimmune diabetes of adults in late stage, insulin glargine needs the support of fast acting insulin taken with food to reduce the effect of prandially derived glucose.
Insulin Glargine Market is formulated at an acidic pH 4, where it is completely water-soluble. After subcutaneous injection of the acidic solute, when a physiologic pH (approximately 7.4) is achieved the increase in pH causes the insulin to come out of solution resulting in the formation of higher order aggregates of insulin hexamers.
The higher order aggregation slows the dissociation of the hexamers into insulin monomers, the functional and physiologically active unit of insulin. This gradual process ensures that small amounts of insulin glargine are released into the body continuously, giving an almost peakless profile.
Insulin Glargine Market is produced by recombinant DNA technology using a non-pathogenic laboratory strain of Escherichia coli (K12) as the production organism. It is an analogue of human insulin made by replacing the asparagine residue at position A21 of the A-chain with glycine and adding two arginines to the C-terminus (positions B31 and 32) of the B-chain. The resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4. Small amounts of insulin glargine are slowly released from microprecipitates giving the drug a long duration of action (up to 24 hours) and no pronounced peak concentration.
Insulin glargine is a prescription medication used to treat type 1 and type 2 diabetes. Insulin glargine, a long-acting form of insulin, works by replacing the insulin that is normally produced by the body and by helping the body to use sugar for energy. It also stops the liver from producing more sugar.
This medication comes in an injectable form to be injected under the skin (subcutaneously). Insulin glargine is usually injected once daily.
Common side effects include low blood sugar, redness and skin thickening at the injection site, and weight gain.
On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split into - Single Dose Vial, Pre-filled Syringe.
On the basis of the end users/applications, this report focuses on the status and outlook for major applications/end users, consumption (sales), market share and growth rate for each application, including - Treat Type 1 Diabetes, Treat Type 2 Diabetes.
Access Complete Report at https://www.businessindustryreports.com/report/83975/global-insulin-glargine-market-research-report-2018 .
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